Co-Amorphization of Ibuprofen by Paracetamol for Improved Processability, Solubility, and In vitro Dissolution
نویسندگان
چکیده
منابع مشابه
study of cohesive devices in the textbook of english for the students of apsychology by rastegarpour
this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
Effects of Spray Drying and Spray Chilling on Ibuprofen Dissolution
The formulation of hydrophobic drugs for oral drug delivery is challenging due to poor solubility, poor dissolution and poor wetting of these drugs. Consequently, the aim of this study was to improve the dissolution of a model poorly water soluble drug, ibuprofen. Microparticles containing ibuprofen were produced by spray drying and spray chilling technology in the absence/presence of a ...
متن کاملDetermination of Solubility Parameters of Ibuprofen and Ibuprofen Lysinate.
In recent years there has been a growing interest in formulating solid dispersions, which purposes mainly include solubility enhancement, sustained drug release and taste masking. The most notable problem by these dispersions is drug-carrier (in)solubility. Here we focus on solubility parameters as a tool for predicting the solubility of a drug in certain carriers. Solubility parameters were de...
متن کاملTreating fever in children: paracetamol or ibuprofen?
Community health practitioners frequently prescribe or advise parents on antipyretic medications for children with fevers. This mini-review sets out to examine the evidence for the relative effectiveness of two of the most widely available and commonly used over-the-counter medicines - paracetamol and ibuprofen. A systematic literature search was undertaken to identify all studies comparing the...
متن کاملRandomised controlled trial of combined paracetamol and ibuprofen for fever.
A randomised open label study of the combined use of paracetamol and ibuprofen to rapidly reduce fever is reported. The advantage of using both medications is less than half a degree centigrade in the first hour, and insufficient to warrant routine use.
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ژورنال
عنوان ژورنال: Acta Chimica Slovenica
سال: 2018
ISSN: 1580-3155
DOI: 10.17344/acsi.2017.3822